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学術雑誌・研究業績
Xenopus laevis 提供:Kato-S-Science
検索:Kato-S-Science ↓
■ Effects
of nonylphenol and triclosan on production of plasma vitellogenin
and testosterone in male South African clawed frogs (Xenopus
laevis)
■
[PDF]
jst.go.jp
N Matsumura, H Ishibashi,
M Hirano... - Biological and... , 2005-jstage.jst.go.jpq ...
Chiba,Japan, and have been maintained in glass
tanks in our laboratory under 16 h light-8 h
dark photoperiod at 241℃ The frogs were fed a commercial diet
(Kato-S-Science) once dailyduring the acclimatization
period for 7 d. Exposure Design Frogs were exposed to the...
■ Assembly
of Taurine Transporter (Slc6a6) with Na+-H+ Exchanger Regulatory
Factor 1 (Slc9a3r1) Improves GABA Transport Activity by Increasing
the Maximum...
■ [PDF] jst.go.jp
M Tachikawa, R Yokoyama, S Akanuma...-
Biological and..., 2018 - jstage.jst.go..jp- water. Mature female
Xenopus laevis frogs were obtained from Kato-S-Science(Chiba,Japan).
All experiments were approved by the Animal Care Committee at
the University of Toyama and Tohoku University. Glutathione...
■ Pharmacokinetics
and metabolism of [14C]anagliptin, a novel dipeptidyl peptidase-4
inhibitor, in humans
S Furuta, C Smart, A Hackett, R
Benning...- Xenobiotica, 2013 - Taylor & Francis... The Xenopus
laevis were purchased from Kato-S-Science(Chiba.Japan),
and human organic
anion transporters... MG, 4.6×250 mm, 5μm; Nomura Chemical, Aichi,
Japan) under linear.. Plasma concentration-time profile of anagliptin
was similar with Japanese healthy men at...
■ [HTML] ...-Aminobutyric
acid transporter 2 mediates the hepatic uptake of guanidinoacetate,
the creatine biosynthetic precursor, in rats
■ M Tachikawa, S Ikeda, J Fujinawa,
S Hirose...- PloS one, 2012 - journals.plos..org... Mature female
Xenopus laevis were purchased from Kato-S-Science
(Chiba,Japan) and maintained in a controlled environment.
All experiments were approved by the Animal Care Committee, University
of Toyama (Protocol# S2008PHA-1, A2011PHA-15, A2011PHA-16)...
■ Role
of the blood-cerebrospinal fluid barrier transporter as a cerebral
clearance system for prostaglandin E2 produced in the brain
M Tachikawa, G Ozeki, T Higuchi...- Journal of..., 2012 - Wiley
Online Library...Materials and methods. Animals. Adult male ddY
mice (25-30 g), Wistar rats (260-280 g), and female Hartley guinea
pigs (300-350 g) were purchased from Japan SLC (Hamamatsu, Japan).
Mature female Xenopus laevis were purchased from Kato-S-Science
(Chiba,Japan)
...
■ Edoxaban
transport via P-glycoprotein is a key factor for the drug's disposition
T Mikkaichi, Y Yoshigae, H Masumoto, T Imaoka...- Drug Metabolism
and..., 2014 - ASPET
■ [HTML]
Doxepin
and imipramine but not fluoxetine reduce the activity of the
rat glutamate transporter EAAT3 expressed in Xenopus oocytes
HJ Park, HJ Baik, DY Kim...- BMC..., 2015 - bmcanesthesiol.biomedcentral..com...animals.
Mature female Xenopus laevis frogs were purchased from Kato
S Science (Chiba, Japan) and fed regular frog brittle twice
weekly. All reagents, unless specified below, were obtained from
Sigma (St. Louis, MO, USA)...
■ Anatomical
integration of the sacral-hindlimb unit coordinated by GDF11
underlies variation in hindlimb positioning in tetrapods
Y Matsubara, T Hirasawa, S Egawa, A Hattori...- Nature Ecology
&..., 2017 - nature..com Elucidating how body parts from
different primordia are integrated during development is essential
for understanding the nature of morphological evolution. In tetrapod
evolution, while the position of the hindlimb has diversified
along with the vertebral formula, the mechanism responsible...
■ 1,
10-Phenanthroline phosphorylates (activates) MAP kinase in Xenopus
oocytes
KI Watanabe,T Tokumoto, K Ishikawa- Cellular signalling, 2003
- Elsevier...has not previously been addressed. 2. Materials
and methods. 2.1. Animals. Adult females of Xenopus laevis
(Kato-S-Science, Japan) were bred and fed in our laboratory
until used. 2.2. Materials. Progesterone, ZnSO 4 , 1,10...
■ Free
from Publisher Organic anion transporting polypeptide (OATP)
2B1 contributes to gastrointestinal toxicity of anticancer drug
SN-38, active metabolite of irinotecan hydrochloride
■ [HTML] aspetjournals.org
D Fujita, Y Saito,T Nakanishi, I Tamai- Drug Metabolism and Disposition,
2016 - ASPET
■ Monocarboxylate
transporter 12 as a guanidinoacetate efflux transporter in renal
proximal tubular epithelial cells
R Jomura, Y Tanno, S Akanuma,Y Kubo...- ...et Biophysica Acta
(BBA..., 2020 - Elsevier...study. Mature female Xenopus laevis
frogs were purchased from Kato-S-Science (Chiba, Japan).
Male Wistar/ST rats (150-180 g) and female Hartley guinea pigs(300-350
g) were purchased from Japan SLC (Shizuoka, Japan)...
■ Novel
indole and benzothiophene ring derivatives showing differential
modulatory activity against human epithelial sodium channel subunits,
ENaCβandγ
Y Kasahara, T Sakurai, R Matsuda...- Bioscience..., 2019 - Taylor
& Francis... Female Xenopus laevis (> 130 g) was purchased
from Kato S science (Chiba, Japan) and kept at a water
temperature of approximately 16℃-. Oocytes were collected following
incision of the lower abdomen and placed in 15 ml collection
vials with MBS solution (88 mM NaCl, 1...
■ Iron
uptake mediated by the plant-derived chelator nicotianamine in
the small intestine
■ [PDF]
jbc.org
Y Murata, M Yoshida, N Sakamoto, S Morimoto...- Journal of Biological...,
2020 - ASBMB... X. laevis (Kato-S Science, Chiba, Japan)
oocytes were voltage-clamped at -60 mV with an OC-725C oocyte
clamp (Warner Instruments, Hamden, CT, USA) and were placed in
an open chamber with continuous perfusion of ND96 buffer (pH
6.0) or ND96-containing substrates...
■ A
clearance system for prostaglandin D2, a sleep-promoting factor,
in cerebrospinal fluid: role of the blood-cerebrospinal barrier
transporters
M Tachikawa, K Tsuji, R Yokoyama, T Higuchi...- ...of Pharmacology
and..., 2012 - ASPET
■ Organic
anion-transporting polypeptide 1a4-mediated heterogeneous distribution
of sulforhodamine-101 in rat hepatic lobules
S Akanuma, R Kida, A Tsuchiyama...- Drug metabolism and..., 2019
- Elsevier... light cycle. Mature female X. laevis frogs were
obtained from Kato-S-Science (Chiba,Japan) and maintained
in a controlled environment: temperature = -15 ℃; humidity =-50%;
and 12/12 h dark/light cycle. All animal experiments...
■
Inflammation-Induced Attenuation of Prostaglandin D2 Elimination
across Rat BloodミBrain Barrier: Involvement of the Downregulation
of Organic Anion Transporter 3...
[PDF]
jst.go.jp
S Akanuma, K Hashimoto, Y Yoshida...- Biological and..., 2020
- jstage.jst.go.jp...200 g/rat) and X. frogs (female, 140-220
g) were purchased from Japan SLC (Hamamatsu,Japan) and Kato-S-
Science (Chiba, Japan), respectively. The rats were maintained
with a 12/12 h dark/light cycle in a controlled environment:
humidity, approx...
■ Full
View The blood-cerebrospinal fluid barrier is a major pathway
of cerebral creatinine clearance: involvement of transporter-mediated
process
M Tachikawa, Y Kasai, M Takahashi...- Journal of..., 2008 - Wiley
Online Library... Mature female Xenopus laevis were purchased
from Kato-S-Science (Chiba, Japan) and maintained in a
controlled environment. All experiments were approved by the
Animal Care Committee, University of Toyama. Reagents...
■ Analysis
of a sperm surface molecule that binds to a vitelline envelope
component of Xenopus laevisハeggs
H Kubo, K Shiga, Y Harada...- Molecular reproduction and...,
2010 - Wiley Online Library...Sexually mature males and females
of X. laevis were obtained from a dealer
(Kato-S-Science,Chiba, Japan) and maintained at 20℃. Protein
concentration was estimated using bicinchoninic acid (BCA) protein
assay reagents (Pierce, Rockford, IL) with bovine serum albumin...
■ Renal
Reabsorptive Transport of Uric Acid Precursor Xanthine by URAT1
and GLUT9
■ [PDF]jst.go.jp
H Arakawa, N Amezawa, Y Kawakatsu...- Biological and.., 2020
- jstage.jst.go.jp... Dotinurad and topiroxostat were obtained
from Fuji Yakuhin Co., Ltd. (Saitama, Japan). All other chemicals
were commercial prod- ucts of reagent grade. Uptake Study by
Xenopus Oocyte Xenopus laevis frogs were obtained from Kato-S-Science
(Chiba, Japan)...
■ Expression
and possible role of creatine transporter in the brain and at
the blood?cerebrospinal fluid barrier as a transporting protein
of guanidinoacetate, an...
M Tachikawa, J Fujinawa, M Takahashi..- Journal of..., 2008 -
Wiley Online Library... Mature female Xenopus laevis were purchased
from Kato-S-Science (Chiba, Japan) and maintained in a
controlled environment. All experiments were approved by the
Animal Care Committee, University of Toyama. Reagents...
■ The
bloodーbrain barrier transport and cerebral distribution of guanidinoacetate
in rats: involvement of creatine and taurine transporters
M Tachikawa, Y Kasai, R Yokoyama...- Journal of..., 2009 - Wiley
Online Library.. Mature female Xenopus laevis were purchased
from Kato-S-Science (Chiba, Japan) and maintained in a
controlled environment. All experiments were approved by the
Animal Care Committee, University of Toyama. Reagents...
■ Molecular
localization and characterization of multiple binding sites of
organic anion transporting polypeptide 2B1 (OATP2B1) as the mechanism
for substrate and....
Y Hoshino, D Fujita, T Nakanishi, I Tamai - MedChemComm, 2016
- pubs.rsc.org...Cycle Sequencing Kit (Applied Biosystems). Transport
study in Xenopus oocytes expressing OATP2B1. Xenopus laevis (African
clawed frogs) were purchased from Kato-S-Science (Chiba, Japan).
Preparation of oocytes, in...
■ Remifentanil
increases the activity of the glutamate transporter, EAAC1, expressed
in Xenopus oocytes
■ [PDF]
anesth-pain-med.org
J Ryu, SH Do, N Lee - Anesthesia and Pain Medicine, 2008 - anesth-pain-med.org...
Procedure for isolation and microinjecion of Xenopus oocytes
was published previously by Do et al.20) Mature female Xenopus
laevis frogs were purchased from Kato S Science (Chiba, Japan),
and fed with regular frog brittle twice weekly...
■ A
novel fluorescence-based method to evaluate ileal apical sodium-dependent
bile acid transporter ASBT
Q Zhu, H Komori, R Imamura, I Tamai- Journal of Pharmaceutical
Sciences, 2020 - Elsevier...Louis, MO), or Kanto Chemicals Co.,
Inc. (Tokyo). Caco-2 cell and female Xenopus laevis frogs were
purchased from RIKEN Cell Bank (Tsukuba, Japan) and Kato-S-Science
(Chiba, Japan), respectively. Transport experiments with
Xenopus laevis oocytes...
■ Na+-Independent
Choline Transport in Rat Retinal Capillary Endothelial Cells
M Tomi, K Arai, M Tachikawa, K Hosoya- Neurochemical Research,
2007 - Springer... Experimental procedure. Animals. Male Wistar
rats, weighing 250-300g, were purchased from SLC (Shizuoka, Japan).
Mature female Xenopus laevis frogs were purchased from Kato-S-Science
(Chiba, Japan). The investigations...
■ 17β-Estradiol
attenuates the activity of the glutamate transporter type 3 expressed
in Xenopus oocytes
HS Na, HP Park, CS Kim, SH Do,Z Zuo...- European journal of...,
2012 - Elsevier... Mature female Xenopus laevis frogs were purchased
from Kato S Science (Chiba, Japan),and fed with regular
frog brittle twice weekly. Molecular biology reagents were obtained
from Ambion (Austin, TX), and other chemicals from Sigma...
■
Corticosterone decreases the activity of rat glutamate transporter
type 3 expressed in Xenopus oocytes
M Kang, J Ryu, JH Kim, H Na,Z Zuo, SH Do- Steroids, 2010 - Elsevier...
The molecular biologic reagents were obtained from Promega (Madison,
WI, USA). Mature female Xenopus laevis frogs were purchased from
Kato S Science (Chiba, Japan),unless specified in the
text...
- News -
■ カエルを実験しノーベル生理学・医学賞受賞者(歴史)
1905年コッホ(ドイツ)結核に関する研究・1920年クローグ(デンマーク)毛細血管運動に関する調整機構の発見・1922年マイヤーホフ(ドイツ)筋肉の酸素消費と乳酸代謝の定式的関係の発見・1936年レーヴィ(アメリカ)神経刺激の化学的伝達に関する発見・1944年アーランガー(アメリカ)個々の神経繊維の高度に分化された機能に関する諸発見...(参考資料:ノーベル生理学・医学賞受賞
と動物実験)
■ 2016年ノーベル生理学・医学賞受賞 東京工業大学大隅良典栄誉教授
1994年創業し一番最初に、助言・情報等を頂き提供させて頂いたのが、同大学の岸本・大隅研究室でした。
■ 2018年ノーベル生理学・医学賞受賞 京都大学本庶佑特別教授
71年にブラウン博士の元に留学しカエルの遺伝子研究を行った。シアトルからブラウン博士の元に来て活躍中だった分子生物学者ロン.リーダー博士とアフリカツメガエル雑種胚のリボソームRNA遺伝子発見について研究し、英国トップクラスの分子生物雑誌で発表。(新聞コラム原稿:「街
ひと 自然 」カエル博士が語るから)
■ ジョン・ガードン博士関連 (Johon B.Gurdon)
■ 情報提供:東京大学(名誉教授)帝京大学理工学部(客員教授)アジア日本語学院(学院長)福岡医療専門学校 塩川光一郎先生
■ 2012年ノーベル生理学・医学賞受賞共同受賞:ジョン・ガードン博士・iPS細胞 京都大学山中 伸弥教授
■ アフリカツメガエルを用いてクーロン動物を世界で最初に確立:ケンブリッジ大学教授・ガードン研究所/所長ジョン・ガードン博士を2005年11月帝京大学理工学部に学長のゲストとしてお呼びし「遺伝子とクーロン動物」の特別公開講義
■ 2012年度ノーベル賞受賞記念出版
「ガードン卿:その研究と人柄の魅力」塩川光一郎(本になる前の原稿の一部)
■ 2017年度筑豊博物研究会雑誌原稿
第62号平成29年12月号掲載予定の原稿(出版者:筑豊博物研究会)アフリカツメガエル発生学研究の紹介
(1) ジョン・ガードン博士のノーベル賞研究(核移植)を中心として
■ 医学生理学に貢献するアフリカツメガエル(新聞コラム原稿:「街 ひと 自然 」カエル博士が語るから)
■ ギリシャのクレタ島での第16回
アフリカツメガエル国際会議(原稿の一部)
■ アフリカツメガエル歴史の一部(新聞コラム原稿の一部:「街 ひと 自然 」カエル博士が語るから)
■ 柔整ホットニュース ビッグインタビュー
■ 電子書籍出版の計画
■ 生命科学を学ぶ人におくる大学基礎生物学 塩川光一郎(著)(塩川先生 から本を出版したと連絡を頂きました)
■ 作品一覧 塩川光一郎(著)
■ 単行本検索 塩川光一郎(著)
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